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Prenatal administration of IL-1Ra attenuate the neurodevelopmental impacts following non-pathogenic inflammation during pregnancy

Prenatal inflammation negatively affects placental function, subsequently altering fetal development. Pathogen-associated molecular patterns (PAMPs) are used to mimics infections in preclinical models but rarely detected during pregnancy. Our group previously developed an animal model of prenatal ex...

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Detalles Bibliográficos
Autores principales: Brien, Marie-Eve, Hughes, Katia, Girard, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642433/
https://www.ncbi.nlm.nih.gov/pubmed/34862457
http://dx.doi.org/10.1038/s41598-021-02927-3