Bruceine D inhibits HIF-1α-mediated glucose metabolism in hepatocellular carcinoma by blocking ICAT/β-catenin interaction

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths, characterized by highly hypoxic tumor microenvironment. Hypoxia-inducible factor-1α (HIF-1α) is a major regulator involved in cellular response to changes of oxygen levels, supporting the adaptation of tumor cells...

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Detalles Bibliográficos
Autores principales: Huang, Rui, Zhang, Lijun, Jin, Jinmei, Zhou, Yudong, Zhang, Hongwei, Lv, Chao, Lu, Dong, Wu, Ye, Zhang, Hong, Liu, Sanhong, Chen, Hongzhuan, Luan, Xin, Zhang, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642446/
https://www.ncbi.nlm.nih.gov/pubmed/34900531
http://dx.doi.org/10.1016/j.apsb.2021.05.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642446/
https://www.ncbi.nlm.nih.gov/pubmed/34900531
http://dx.doi.org/10.1016/j.apsb.2021.05.009

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