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Bruceine D inhibits HIF-1α-mediated glucose metabolism in hepatocellular carcinoma by blocking ICAT/β-catenin interaction
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths, characterized by highly hypoxic tumor microenvironment. Hypoxia-inducible factor-1α (HIF-1α) is a major regulator involved in cellular response to changes of oxygen levels, supporting the adaptation of tumor cells...
Autores principales: | Huang, Rui, Zhang, Lijun, Jin, Jinmei, Zhou, Yudong, Zhang, Hongwei, Lv, Chao, Lu, Dong, Wu, Ye, Zhang, Hong, Liu, Sanhong, Chen, Hongzhuan, Luan, Xin, Zhang, Weidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642446/ https://www.ncbi.nlm.nih.gov/pubmed/34900531 http://dx.doi.org/10.1016/j.apsb.2021.05.009 |
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