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High-intensity training induces non-stoichiometric changes in the mitochondrial proteome of human skeletal muscle without reorganisation of respiratory chain content

Mitochondrial defects are implicated in multiple diseases and aging. Exercise training is an accessible, inexpensive therapeutic intervention that can improve mitochondrial bioenergetics and quality of life. By combining multiple omics techniques with biochemical and in silico normalisation, we remo...

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Detalles Bibliográficos
Autores principales: Granata, Cesare, Caruana, Nikeisha J., Botella, Javier, Jamnick, Nicholas A., Huynh, Kevin, Kuang, Jujiao, Janssen, Hans A., Reljic, Boris, Mellett, Natalie A., Laskowski, Adrienne, Stait, Tegan L., Frazier, Ann E., Coughlan, Melinda T., Meikle, Peter J., Thorburn, David R., Stroud, David A., Bishop, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642543/
https://www.ncbi.nlm.nih.gov/pubmed/34862379
http://dx.doi.org/10.1038/s41467-021-27153-3