Depletion of m(6)A reader protein YTHDC1 induces dilated cardiomyopathy by abnormal splicing of Titin

N (6)‐methyladenosine (m(6)A) is the most prevalent modification in mRNA and engages in multiple biological processes. Previous studies indicated that m(6)A methyltransferase METTL3 (‘writer’) and demethylase FTO (‘eraser’) play critical roles in heart‐related disease. However, in the heart, the fun...

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Detalles Bibliográficos
Autores principales: Gao, Siyun, Sun, Haifeng, Chen, Kejing, Gu, Xueying, Chen, Hongyu, Jiang, Liudan, Chen, Lei, Zhang, Shengqi, Liu, Yi, Shi, Dan, Liang, Dandan, Xu, Liang, Yang, Jian, Ruan, Yanjiao, Chen, Hao, Shen, Bin, Ma, Honghui, Chen, Yi‐Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642692/
https://www.ncbi.nlm.nih.gov/pubmed/34716659
http://dx.doi.org/10.1111/jcmm.16955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642692/
https://www.ncbi.nlm.nih.gov/pubmed/34716659
http://dx.doi.org/10.1111/jcmm.16955

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