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Depletion of m(6)A reader protein YTHDC1 induces dilated cardiomyopathy by abnormal splicing of Titin
N (6)‐methyladenosine (m(6)A) is the most prevalent modification in mRNA and engages in multiple biological processes. Previous studies indicated that m(6)A methyltransferase METTL3 (‘writer’) and demethylase FTO (‘eraser’) play critical roles in heart‐related disease. However, in the heart, the fun...
Autores principales: | Gao, Siyun, Sun, Haifeng, Chen, Kejing, Gu, Xueying, Chen, Hongyu, Jiang, Liudan, Chen, Lei, Zhang, Shengqi, Liu, Yi, Shi, Dan, Liang, Dandan, Xu, Liang, Yang, Jian, Ruan, Yanjiao, Chen, Hao, Shen, Bin, Ma, Honghui, Chen, Yi‐Han |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642692/ https://www.ncbi.nlm.nih.gov/pubmed/34716659 http://dx.doi.org/10.1111/jcmm.16955 |
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