The Effect of Length and Structure of Attached Polyethylene Glycol Chain on Hydrodynamic Radius, and Separation of PEGylated Human Serum Albumin by Chromatography

Purpose: This study focuses on the effect of length and structure of attached polyethylene glycol (PEG) chain on hydrodynamic radius (R(h) ) and chromatographic retention of PEGylated protein. To this aim human serum albumin (HSA) as a standard protein was PEGylated site specifically with mPEG-malei...

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Detalles Bibliográficos
Autores principales: Akbarzadehlaleh, Parvin, Mirzaei, Mona, Mashahdi-Keshtiban, Mahdiyeh, Heidari, Hamid Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642789/
https://www.ncbi.nlm.nih.gov/pubmed/34888220
http://dx.doi.org/10.34172/apb.2021.082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642789/
https://www.ncbi.nlm.nih.gov/pubmed/34888220
http://dx.doi.org/10.34172/apb.2021.082

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