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DR-5 and DLL-4 mAb Functionalized SLNs of Gamma-Secretase Inhibitors- An Approach for TNBC Treatment

Triple-negative breast cancer (TNBC) is the most aggressive and heterogeneous cancer subtypes. High rates of metastasis, poor prognosis, and drug resistance are the major problems associated with TNBC. The current chemotherapeutics eliminate only the bulk tumor cells (non-BCSCs) and do not affect br...

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Detalles Bibliográficos
Autores principales: Kumari, Mamta, Krishnamurthy, Praveen T., Pinduprolu, Sai kiran S. S., Sola, Piyongsola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642801/
https://www.ncbi.nlm.nih.gov/pubmed/34888208
http://dx.doi.org/10.34172/apb.2021.070