Studying the Effect of Amino Acid Substitutions in the M2 Ion Channel of the Influenza Virus on the Antiviral Activity of the Aminoadamantane Derivative In Vitro and In Silico

Purpose: The aminoadamantane derivative of L-histidyl-1-adamantayl ethylamine hydrochloride (HCl*H-His-Rim) has showed a high inhibition level against influenza A virus strains in vitro. The aim of this work is to search and establish evidence of the direct effect of the drug on influenza A virus pr...

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Detalles Bibliográficos
Autores principales: Garaev, Timur Mansurovich, Odnovorov, Artyom Irorevich, Lashkov, Alexander Aleksandrovich, Grebennikova, Tatiana Vladimirovna, Finogenova, Marina Pavlovna, Sadykova, Galina Kadymovna, Prilipov, Alexei Gennadievich, Timofeeva, Tatiana Anatol'evna, Rubinsky, Sergey Vadimovich, Norkina, Svetlana Nikolaevna, Zhuravleva, Marina Mikhailovna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642805/
https://www.ncbi.nlm.nih.gov/pubmed/34888217
http://dx.doi.org/10.34172/apb.2021.079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642805/
https://www.ncbi.nlm.nih.gov/pubmed/34888217
http://dx.doi.org/10.34172/apb.2021.079

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