SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) protein is essential for viral replication, making it a promising target for antiviral drug and vaccine development. SARS-CoV-2 infected patients exhibit an uncoordinated immune response; however, the underlying mechanisti...

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Detalles Bibliográficos
Autores principales: Nabeel-Shah, Syed, Lee, Hyunmin, Ahmed, Nujhat, Burke, Giovanni L., Farhangmehr, Shaghayegh, Ashraf, Kanwal, Pu, Shuye, Braunschweig, Ulrich, Zhong, Guoqing, Wei, Hong, Tang, Hua, Yang, Jianyi, Marcon, Edyta, Blencowe, Benjamin J., Zhang, Zhaolei, Greenblatt, Jack F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642831/
https://www.ncbi.nlm.nih.gov/pubmed/34901782
http://dx.doi.org/10.1016/j.isci.2021.103562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642831/
https://www.ncbi.nlm.nih.gov/pubmed/34901782
http://dx.doi.org/10.1016/j.isci.2021.103562

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