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SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) protein is essential for viral replication, making it a promising target for antiviral drug and vaccine development. SARS-CoV-2 infected patients exhibit an uncoordinated immune response; however, the underlying mechanisti...
Autores principales: | Nabeel-Shah, Syed, Lee, Hyunmin, Ahmed, Nujhat, Burke, Giovanni L., Farhangmehr, Shaghayegh, Ashraf, Kanwal, Pu, Shuye, Braunschweig, Ulrich, Zhong, Guoqing, Wei, Hong, Tang, Hua, Yang, Jianyi, Marcon, Edyta, Blencowe, Benjamin J., Zhang, Zhaolei, Greenblatt, Jack F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642831/ https://www.ncbi.nlm.nih.gov/pubmed/34901782 http://dx.doi.org/10.1016/j.isci.2021.103562 |
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