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MMP12 knockout prevents weight and muscle loss in tumor-bearing mice

BACKGROUND: Colorectal cancer is a malignant gastrointestinal cancer, in which some advanced patients would develop cancer cachexia (CAC). CAC is defined as a multi-factorial syndrome characterized by weight loss and muscle loss (with or without fat mass), leading to progressive dysfunction, thereby...

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Detalles Bibliográficos
Autores principales: Jiang, Lingbi, Yang, Mingming, He, Shihui, Li, Zhengyang, Li, Haobin, Niu, Ting, Xie, Dehuan, Mei, Yan, He, Xiaodong, Wei, Lili, Huang, Pinzhu, Huang, Mingzhe, Zhang, Rongxin, Wang, Lijing, Li, Jiangchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642861/
https://www.ncbi.nlm.nih.gov/pubmed/34863141
http://dx.doi.org/10.1186/s12885-021-09004-y