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Novel approaches in cancer treatment: preclinical and clinical development of small non-coding RNA therapeutics

Short or small interfering RNAs (siRNAs) and microRNA (miRNAs) are molecules similar in size and function able to inhibit gene expression based on their complementarity with mRNA sequences, inducing the degradation of the transcript or the inhibition of their translation. siRNAs bind specifically to...

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Detalles Bibliográficos
Autores principales: Cuciniello, Rossana, Filosa, Stefania, Crispi, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642961/
https://www.ncbi.nlm.nih.gov/pubmed/34863235
http://dx.doi.org/10.1186/s13046-021-02193-1