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Novel approaches in cancer treatment: preclinical and clinical development of small non-coding RNA therapeutics
Short or small interfering RNAs (siRNAs) and microRNA (miRNAs) are molecules similar in size and function able to inhibit gene expression based on their complementarity with mRNA sequences, inducing the degradation of the transcript or the inhibition of their translation. siRNAs bind specifically to...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642961/ https://www.ncbi.nlm.nih.gov/pubmed/34863235 http://dx.doi.org/10.1186/s13046-021-02193-1 |