Cargando…

Novel approaches in cancer treatment: preclinical and clinical development of small non-coding RNA therapeutics

Short or small interfering RNAs (siRNAs) and microRNA (miRNAs) are molecules similar in size and function able to inhibit gene expression based on their complementarity with mRNA sequences, inducing the degradation of the transcript or the inhibition of their translation. siRNAs bind specifically to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cuciniello, Rossana, Filosa, Stefania, Crispi, Stefania
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642961/ https://www.ncbi.nlm.nih.gov/pubmed/34863235 http://dx.doi.org/10.1186/s13046-021-02193-1

Ejemplares similares

Correction to: Novel approaches in cancer treatment: preclinical and clinical development of small non-coding RNA therapeutics
por: Cuciniello, Rossana, et al.
Publicado: (2021)

The Antioxidant Effect of Dietary Bioactives Arises from the Interplay between the Physiology of the Host and the Gut Microbiota: Involvement of Short-Chain Fatty Acids
por: Cuciniello, Rossana, et al.
Publicado: (2023)

An Overview of the Enhanced Effects of Curcumin and Chemotherapeutic Agents in Combined Cancer Treatments
por: Cacciola, Nunzio Antonio, et al.
Publicado: (2023)

Ginkgo biloba Prevents Oxidative Stress-Induced Apoptosis Blocking p53 Activation in Neuroblastoma Cells
por: Di Meo, Francesco, et al.
Publicado: (2020)

Novel perspectives for neurodegeneration prevention: effects of bioactive polyphenols
por: Crispi, Stefania, et al.
Publicado: (2020)

Organic extract of Geodia cydonium induces cell cycle block in human mesothelioma cells
por: Di Meo, Francesco, et al.
Publicado: (2022)

Aglianico Grape Seed Semi-Polar Extract Exerts Anticancer Effects by Modulating MDM2 Expression and Metabolic Pathways
por: Cuciniello, Rossana, et al.
Publicado: (2023)

Polyphenols-gut microbiota interplay and brain neuromodulation
por: Filosa, Stefania, et al.
Publicado: (2018)

Bioactive Polyphenols and Neuromodulation: Molecular Mechanisms in Neurodegeneration
por: Di Meo, Francesco, et al.
Publicado: (2020)

Small non-coding RNA therapeutics for cardiovascular disease
por: Shah, Ajay M, et al.
Publicado: (2022)

Targeting Non-Coding RNAs for the Development of Novel Hepatocellular Carcinoma Therapeutic Approaches
por: Jesenko, Tanja, et al.
Publicado: (2023)

Preclinical and Clinical Development of Noncoding RNA Therapeutics for Cardiovascular Disease
por: Huang, Cheng-Kai, et al.
Publicado: (2020)

Curcumin C3 complex®/Bioperine® has antineoplastic activity in mesothelioma: an in vitro and in vivo analysis
por: Di Meo, Francesco, et al.
Publicado: (2019)

tRNA-Derived Small RNA: A Novel Regulatory Small Non-Coding RNA
por: Li, Siqi, et al.
Publicado: (2018)

Novel non-coding RNA-based therapeutic approaches to prevent statin-induced liver damage
por: Bang, Claudia, et al.
Publicado: (2012)

Microbiota in vivo imaging approaches to study host-microbe interactions in preclinical and clinical setting
por: Campisciano, Giuseppina, et al.
Publicado: (2022)

Preclinical Development of siRNA Therapeutics for AL Amyloidosis
por: Hovey, Beth M., et al.
Publicado: (2011)

Recent advances in exosomal non‐coding RNA‐based therapeutic approaches for photoaging
por: Li, Kun‐Jie, et al.
Publicado: (2023)

Next RNA Therapeutics: The Mine of Non-Coding
por: Garbo, Sabrina, et al.
Publicado: (2022)

Small non‐coding RNA and colorectal cancer
por: Chen, Hui, et al.
Publicado: (2019)

Small Non-Coding-RNA in Gynecological Malignancies
por: Dwivedi, Shailendra Kumar Dhar, et al.
Publicado: (2021)

MicroRNA-934 is a novel primate-specific small non-coding RNA with neurogenic function during early development
por: Prodromidou, Kanella, et al.
Publicado: (2020)

Long Non-Coding RNA Landscape in Prostate Cancer Molecular Subtypes: A Feature Selection Approach
por: De Summa, Simona, et al.
Publicado: (2021)

ATRT-11. DEVELOPMENT OF NOVEL PRECLINICAL MODELS AND THERAPEUTIC STRATEGIES FOR ETMR
por: Cocito, Carolina, et al.
Publicado: (2023)

Non-coding RNA-Associated Therapeutic Strategies in Atherosclerosis
por: Tang, Yuyan, et al.
Publicado: (2022)

Non-Coding RNA: Role in Gestational Diabetes Pathophysiology and Complications
por: Filardi, Tiziana, et al.
Publicado: (2020)

Preclinical validation of the small molecule drug quininib as a novel therapeutic for colorectal cancer
por: Murphy, Adrian G., et al.
Publicado: (2016)

Novel Therapeutic Approaches to Familial HLH (Emapalumab in FHL)
por: Merli, Pietro, et al.
Publicado: (2020)

Small non-coding RNA deregulation in endometrial carcinogenesis
por: Ravo, Maria, et al.
Publicado: (2015)

A General Overview on Non-coding RNA-Based Diagnostic and Therapeutic Approaches for Liver Diseases
por: Roy, Sanchari, et al.
Publicado: (2018)

Targeting non-coding RNA H19: A potential therapeutic approach in pulmonary diseases
por: Xie, Jinghui, et al.
Publicado: (2022)

Computational Approaches in Detecting Non- Coding RNA
por: Wang, Chunyu, et al.
Publicado: (2013)

Non-Invasive Approach for Evaluation of Pulmonary Hypertension Using Extracellular Vesicle-Associated Small Non-Coding RNA
por: Lipps, Christoph, et al.
Publicado: (2019)

Long non-coding RNA H19, a novel therapeutic target for pancreatic cancer
por: Wang, Jing, et al.
Publicado: (2020)

Preclinical and Early Clinical Development of PTC596, a Novel Small-Molecule Tubulin-Binding Agent
por: Jernigan, Finith, et al.
Publicado: (2021)

Identification of a Novel Small Non-Coding RNA Modulating the Intracellular Survival of Brucella melitensis
por: Wang, Yufei, et al.
Publicado: (2015)

tRNA-Derived Small Non-Coding RNAs as Novel Epigenetic Molecules Regulating Adipogenesis
por: Shen, Linyuan, et al.
Publicado: (2019)

Transfer RNA-derived small RNA: an emerging small non-coding RNA with key roles in cancer
por: Gu, Xinliang, et al.
Publicado: (2022)

Long Non-coding RNA Small Nucleolar RNA Host Gene 14, a Promising Biomarker and Therapeutic Target in Malignancy
por: Shen, Shen, et al.
Publicado: (2021)

Therapeutic Potential of Fingolimod and Dimethyl Fumarate in Non-Small Cell Lung Cancer Preclinical Models
por: Rupp, Tristan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_osvlol71rg8bgmpnj40u44k34f