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Safety and efficacy of C1-inhibitor in traumatic brain injury (CIAO@TBI): study protocol for a randomized, placebo-controlled, multi-center trial

BACKGROUND: Traumatic brain injury (TBI) is a major cause of death and disability across all ages. After the primary impact, the pathophysiologic process of secondary brain injury consists of a neuroinflammation response that critically leads to irreversible brain damage in the first days after the...

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Detalles Bibliográficos
Autores principales: van Erp, Inge A. M., van Essen, Thomas A., Fluiter, Kees, van Zwet, Erik, van Vliet, Peter, Baas, Frank, Haitsma, Iain, Verbaan, Dagmar, Coert, Bert, de Ruiter, Godard C. W., Moojen, Wouter A., van der Jagt, Mathieu, Peul, Wilco C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642972/
https://www.ncbi.nlm.nih.gov/pubmed/34863258
http://dx.doi.org/10.1186/s13063-021-05833-1