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Functions of 1,25-dihydroxy vitamin D3, vitamin D3 receptor and interleukin-22 involved in pathogenesis of gout arthritis through altering metabolic pattern and inflammatory responses

BACKGROUND: Gouty arthritis (GA) is a common type of inflammatory arthritis. Recent studies demonstrated that 1,25-dihydroxy vitamin D3 (1,25(OH) 2 VD3) and vitamin D3 receptor (VD-R) play a protective role in acute inflammation, but interleukin-22(IL-22) promotes inflammation, especially for arthri...

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Detalles Bibliográficos
Autores principales: Chen, Yuqi, Ma, Huiya, Du, Youwei, Dong, Jianjian, Jin, Chenkai, Tan, Lihui, Wei, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643101/
https://www.ncbi.nlm.nih.gov/pubmed/34917427
http://dx.doi.org/10.7717/peerj.12585