Gene replacement strategies validate the use of functional tags on centromeric chromatin and invalidate an essential role for CENP-A(K124ub)

Functional tags are ubiquitous in cell biology, and for studies of one chromosomal locus, the centromere, tags have been remarkably useful. The centromere directs chromosome inheritance at cell division. The location of the centromere is defined by a histone H3 variant, CENP-A. The regulation of the...

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Detalles Bibliográficos
Autores principales: Salinas-Luypaert, Catalina, Allu, Praveen Kumar, Logsdon, Glennis A., Dawicki-McKenna, Jennine M., Gambogi, Craig W., Fachinetti, Daniele, Black, Ben E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643106/
https://www.ncbi.nlm.nih.gov/pubmed/34731637
http://dx.doi.org/10.1016/j.celrep.2021.109924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643106/
https://www.ncbi.nlm.nih.gov/pubmed/34731637
http://dx.doi.org/10.1016/j.celrep.2021.109924

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