The Pharmacokinetic Effect of Itraconazole and Voriconazole on Ripretinib in Beagle Dogs by UPLC-MS/MS Technique

BACKGROUND: A new UPLC-MS/MS technique for the determination of ripretinib in beagle dog plasma was developed, and the pharmacokinetic effects of voriconazole and itraconazole on ripretinib in beagle dogs were studied. METHODS: After extraction with ethyl acetate under alkaline conditions, ripretini...

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Detalles Bibliográficos
Autores principales: Wang, Hui-jun, Zhou, Chun-yan, Su, Yan-ding, Gou, Kai-feng, Geng, Xiao-nan, Qiu, Xiang-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643159/
https://www.ncbi.nlm.nih.gov/pubmed/34876808
http://dx.doi.org/10.2147/DDDT.S337864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643159/
https://www.ncbi.nlm.nih.gov/pubmed/34876808
http://dx.doi.org/10.2147/DDDT.S337864

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