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Dexmedetomidine attenuates haemorrhage-induced thalamic pain by inhibiting the TLR4/NF-κB/ERK1/2 pathway in mice

BACKGROUND: Thalamic pain, a neuropathic pain syndrome, frequently occurs after stroke. This research aimed to investigate the effect of dexmedetomidine (DEX) on thalamic pain. METHODS: The cellular localization of the TLR4 protein was determined by immunostaining. The expression of Iba1, GFAP and p...

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Detalles Bibliográficos
Autores principales: Huang, Tianfeng, Li, Yong, Hu, Wenqing, Yu, Dapeng, Gao, Ju, Yang, Fan, Xu, Yingying, Wang, Zehua, Zong, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643300/
https://www.ncbi.nlm.nih.gov/pubmed/34643849
http://dx.doi.org/10.1007/s10787-021-00877-w