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Differentiation therapy for myeloid malignancies: beyond cytotoxicity

Blocked cellular differentiation is a central pathologic feature of the myeloid malignancies, myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). Treatment regimens promoting differentiation have resulted in incredible cure rates in certain AML subtypes, such as acute promyelocytic leuk...

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Detalles Bibliográficos
Autores principales: Stubbins, Ryan J., Karsan, Aly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643352/
https://www.ncbi.nlm.nih.gov/pubmed/34864823
http://dx.doi.org/10.1038/s41408-021-00584-3