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Association of low-frequency and rare coding variants with information processing speed

Measures of information processing speed vary between individuals and decline with age. Studies of aging twins suggest heritability may be as high as 67%. The Illumina HumanExome Bead Chip genotyping array was used to examine the association of rare coding variants with performance on the Digit-Symb...

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Detalles Bibliográficos
Autores principales: Bressler, Jan, Davies, Gail, Smith, Albert V., Saba, Yasaman, Bis, Joshua C., Jian, Xueqiu, Hayward, Caroline, Yanek, Lisa, Smith, Jennifer A., Mirza, Saira S., Wang, Ruiqi, Adams, Hieab H. H., Becker, Diane, Boerwinkle, Eric, Campbell, Archie, Cox, Simon R., Eiriksdottir, Gudny, Fawns-Ritchie, Chloe, Gottesman, Rebecca F., Grove, Megan L., Guo, Xiuqing, Hofer, Edith, Kardia, Sharon L. R., Knol, Maria J., Koini, Marisa, Lopez, Oscar L., Marioni, Riccardo E., Nyquist, Paul, Pattie, Alison, Polasek, Ozren, Porteous, David J., Rudan, Igor, Satizabal, Claudia L., Schmidt, Helena, Schmidt, Reinhold, Sidney, Stephen, Simino, Jeannette, Smith, Blair H., Turner, Stephen T., van der Lee, Sven J., Ware, Erin B., Whitmer, Rachel A., Yaffe, Kristine, Yang, Qiong, Zhao, Wei, Gudnason, Vilmundur, Launer, Lenore J., Fitzpatrick, Annette L., Psaty, Bruce M., Fornage, Myriam, Arfan Ikram, M., van Duijn, Cornelia M., Seshadri, Sudha, Mosley, Thomas H., Deary, Ian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643353/
https://www.ncbi.nlm.nih.gov/pubmed/34864818
http://dx.doi.org/10.1038/s41398-021-01736-6