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Targeting ERK induced cell death and p53/ROS-dependent protective autophagy in colorectal cancer

In recent years, many studies have shown that autophagy plays a vital role in the resistance of tumor chemotherapy. However, the interaction between autophagy and cell death has not yet been clarified. In this study, a new specific ERK inhibitor CC90003 was found to suppress colorectal cancer growth...

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Detalles Bibliográficos
Autores principales: Mi, Wunan, Wang, Chuyue, Luo, Guang, Li, Jiehan, Zhang, Yizheng, Jiang, Meimei, Zhang, Chuchu, Liu, Nannan, Jiang, Xinxiu, Yang, Ge, Zhang, Lingling, Zhang, Ge, Zhang, Yingjie, Fu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643355/
https://www.ncbi.nlm.nih.gov/pubmed/34864826
http://dx.doi.org/10.1038/s41420-021-00677-9