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Targeting ERK induced cell death and p53/ROS-dependent protective autophagy in colorectal cancer
In recent years, many studies have shown that autophagy plays a vital role in the resistance of tumor chemotherapy. However, the interaction between autophagy and cell death has not yet been clarified. In this study, a new specific ERK inhibitor CC90003 was found to suppress colorectal cancer growth...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643355/ https://www.ncbi.nlm.nih.gov/pubmed/34864826 http://dx.doi.org/10.1038/s41420-021-00677-9 |