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Dlg1 Knockout Inhibits Microglial Activation and Alleviates Lipopolysaccharide-Induced Depression-Like Behavior in Mice

Microglia-mediated neuroinflammation is widely perceived as a contributor to numerous neurological diseases and mental disorders including depression. Discs large homolog 1 (Dlg1), an adaptor protein, regulates cell polarization and the function of K(+) channels, which are reported to regulate the a...

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Detalles Bibliográficos
Autores principales: Peng, Zhixin, Li, Xiaoheng, Li, Jun, Dong, Yuan, Gao, Yuhao, Liao, Yajin, Yan, Meichen, Yuan, Zengqiang, Cheng, Jinbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643377/
https://www.ncbi.nlm.nih.gov/pubmed/34490521
http://dx.doi.org/10.1007/s12264-021-00765-x