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Cholesterol modified DP7 and pantothenic acid induce dendritic cell homing to enhance the efficacy of dendritic cell vaccines

Dendritic cell (DC)-based cancer vaccines have so far achieved good therapeutic effects in animal experiments and early clinical trials for certain malignant tumors. However, the overall objective response rate in clinical trials rarely exceeds 15%. The poor efficiency of DC migration to lymph nodes...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Tang, Lin, Li, Qing, Tian, Yaomei, Zhao, Binyan, Zhou, Bailing, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643384/
https://www.ncbi.nlm.nih.gov/pubmed/35006477
http://dx.doi.org/10.1186/s43556-021-00058-9