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Isoform-specific Roles of Prolyl Hydroxylases in the Regulation of Pancreatic β-Cell Function
Pancreatic β-cells can secrete insulin via 2 pathways characterized as K(ATP) channel -dependent and -independent. The K(ATP) channel–independent pathway is characterized by a rise in several potential metabolic signaling molecules, including the NADPH/NADP(+) ratio and α-ketoglutarate (αKG). Prolyl...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643417/ https://www.ncbi.nlm.nih.gov/pubmed/34718519 http://dx.doi.org/10.1210/endocr/bqab226 |