Isoform-specific Roles of Prolyl Hydroxylases in the Regulation of Pancreatic β-Cell Function

Pancreatic β-cells can secrete insulin via 2 pathways characterized as K(ATP) channel -dependent and -independent. The K(ATP) channel–independent pathway is characterized by a rise in several potential metabolic signaling molecules, including the NADPH/NADP(+) ratio and α-ketoglutarate (αKG). Prolyl...

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Detalles Bibliográficos
Autores principales: Hoang, Monica, Jentz, Emelien, Janssen, Sarah M, Nasteska, Daniela, Cuozzo, Federica, Hodson, David J, Tupling, A Russell, Fong, Guo-Hua, Joseph, Jamie W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643417/
https://www.ncbi.nlm.nih.gov/pubmed/34718519
http://dx.doi.org/10.1210/endocr/bqab226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643417/
https://www.ncbi.nlm.nih.gov/pubmed/34718519
http://dx.doi.org/10.1210/endocr/bqab226

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