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Early Initiation of Antiretroviral Therapy Following In Utero HIV Infection Is Associated With Low Viral Reservoirs but Other Factors Determine Viral Rebound

BACKGROUND: Early HIV diagnosis allows combination antiretroviral therapy (cART) initiation in the first days of life following in utero (IU) infection. The impact of early cART initiation on infant viral reservoir size in the setting of high-frequency cART nonadherence is unknown. METHODS: Peripher...

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Detalles Bibliográficos
Autores principales: Millar, Jane R, Bengu, Nomonde, Vieira, Vinicius A, Adland, Emily, Roider, Julia, Muenchhoff, Maximilian, Fillis, Rowena, Sprenger, Kenneth, Ntlantsana, Vuyokazi, Fatti, Isabella, Archary, Moherndran, Groll, Andreas, Ismail, Nasreen, García-Guerrero, Maria C, Matthews, Philippa C, Ndung’u, Thumbi, Puertas, Maria C, Martinez-Picado, Javier, Goulder, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643423/
https://www.ncbi.nlm.nih.gov/pubmed/33963757
http://dx.doi.org/10.1093/infdis/jiab223