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Genomic and pleiotropic analyses of resting QT interval identifies novel loci and overlap with atrial electrical disorders

The resting QT interval, an electrocardiographic (ECG) measure of ventricular myocardial repolarization, is a heritable risk marker of cardiovascular mortality, but the mechanisms remain incompletely understood. Previously reported candidate genes have provided insights into the regulatory mechanism...

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Detalles Bibliográficos
Autores principales: van Duijvenboden, Stefan, Ramírez, Julia, Young, William J, Orini, Michele, Mifsud, Borbala, Tinker, Andrew, Lambiase, Pier D, Munroe, Patricia B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643508/
https://www.ncbi.nlm.nih.gov/pubmed/34274964
http://dx.doi.org/10.1093/hmg/ddab197