Evolutionary repair reveals an unexpected role of the tRNA modification m(1)G37 in aminoacylation

The tRNA modification m(1)G37, introduced by the tRNA methyltransferase TrmD, is thought to be essential for growth in bacteria because it suppresses translational frameshift errors at proline codons. However, because bacteria can tolerate high levels of mistranslation, it is unclear why loss of m(1...

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Detalles Bibliográficos
Autores principales: Clifton, Ben E, Fariz, Muhammad A, Uechi, Gen-Ichiro, Laurino, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643618/
https://www.ncbi.nlm.nih.gov/pubmed/34761260
http://dx.doi.org/10.1093/nar/gkab1067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643618/
https://www.ncbi.nlm.nih.gov/pubmed/34761260
http://dx.doi.org/10.1093/nar/gkab1067

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