Master lineage transcription factors anchor trans mega transcriptional complexes at highly accessible enhancer sites to promote long-range chromatin clustering and transcription of distal target genes

The term ‘super enhancers’ (SE) has been widely used to describe stretches of closely localized enhancers that are occupied collectively by large numbers of transcription factors (TFs) and co-factors, and control the transcription of highly-expressed genes. Through integrated analysis of >600 DNa...

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Detalles Bibliográficos
Autores principales: White, Shannon M, Snyder, Michael P, Yi, Chunling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643643/
https://www.ncbi.nlm.nih.gov/pubmed/34850122
http://dx.doi.org/10.1093/nar/gkab1105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643643/
https://www.ncbi.nlm.nih.gov/pubmed/34850122
http://dx.doi.org/10.1093/nar/gkab1105

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