High resolution copy number inference in cancer using short-molecule nanopore sequencing

Genome copy number is an important source of genetic variation in health and disease. In cancer, Copy Number Alterations (CNAs) can be inferred from short-read sequencing data, enabling genomics-based precision oncology. Emerging Nanopore sequencing technologies offer the potential for broader clini...

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Detalles Bibliográficos
Autores principales: Baslan, Timour, Kovaka, Sam, Sedlazeck, Fritz J, Zhang, Yanming, Wappel, Robert, Tian, Sha, Lowe, Scott W, Goodwin, Sara, Schatz, Michael C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643650/
https://www.ncbi.nlm.nih.gov/pubmed/34551429
http://dx.doi.org/10.1093/nar/gkab812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643650/
https://www.ncbi.nlm.nih.gov/pubmed/34551429
http://dx.doi.org/10.1093/nar/gkab812

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