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Cisplatin fastens chromatin irreversibly even at a high chloride concentration

Cisplatin is one of the most potent anti-cancer drugs developed so far. Recent studies highlighted several intriguing roles of histones in cisplatin's anti-cancer effect. Thus, the effect of nucleosome formation should be considered to give a better account of the anti-cancer effect of cisplati...

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Detalles Bibliográficos
Autores principales: Moon, Hyeon-Min, Park, Jin-Sung, Lee, Il-Buem, Kang, Young-Im, Jung, Hae Jun, An, Dongju, Shin, Yumi, Kim, Min Ji, Kim, Hugh I, Song, Ji-Joon, Kim, Jaehoon, Lee, Nam-Kyung, Hong, Seok-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643659/
https://www.ncbi.nlm.nih.gov/pubmed/34865121
http://dx.doi.org/10.1093/nar/gkab922