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The pioneer round of translation ensures proper targeting of ER and mitochondrial proteins

The pioneer (or first) round of translation of newly synthesized mRNAs is largely mediated by a nuclear cap-binding complex (CBC). In a transcriptome-wide analysis of polysome-associated and CBC-bound transcripts, we identify RN7SL1, a noncoding RNA component of a signal recognition particle (SRP),...

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Detalles Bibliográficos
Autores principales: Park, Joori, Chang, Jeeyoon, Hwang, Hyun Jung, Jeong, Kwon, Lee, Hyuk-Joon, Ha, Hongseok, Park, Yeonkyoung, Lim, Chunghun, Woo, Jae-Sung, Kim, Yoon Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643669/
https://www.ncbi.nlm.nih.gov/pubmed/34850140
http://dx.doi.org/10.1093/nar/gkab1098