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The hyperthermophilic archaeon Thermococcus kodakarensis is resistant to pervasive negative supercoiling activity of DNA gyrase

In all cells, DNA topoisomerases dynamically regulate DNA supercoiling allowing essential DNA processes such as transcription and replication to occur. How this complex system emerged in the course of evolution is poorly understood. Intriguingly, a single horizontal gene transfer event led to the su...

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Detalles Bibliográficos
Autores principales: Villain, Paul, da Cunha, Violette, Villain, Etienne, Forterre, Patrick, Oberto, Jacques, Catchpole, Ryan, Basta, Tamara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643681/
https://www.ncbi.nlm.nih.gov/pubmed/34755863
http://dx.doi.org/10.1093/nar/gkab869