Loss of full-length hnRNP R isoform impairs DNA damage response in motoneurons by inhibiting Yb1 recruitment to chromatin

Neurons critically rely on the functions of RNA-binding proteins to maintain their polarity and resistance to neurotoxic stress. HnRNP R has a diverse range of post-transcriptional regulatory functions and is important for neuronal development by regulating axon growth. Hnrnpr pre-mRNA undergoes alt...

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Detalles Bibliográficos
Autores principales: Ghanawi, Hanaa, Hennlein, Luisa, Zare, Abdolhossein, Bader, Jakob, Salehi, Saeede, Hornburg, Daniel, Ji, Changhe, Sivadasan, Rajeeve, Drepper, Carsten, Meissner, Felix, Mann, Matthias, Jablonka, Sibylle, Briese, Michael, Sendtner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643683/
https://www.ncbi.nlm.nih.gov/pubmed/34850154
http://dx.doi.org/10.1093/nar/gkab1120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643683/
https://www.ncbi.nlm.nih.gov/pubmed/34850154
http://dx.doi.org/10.1093/nar/gkab1120

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