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The human telomeric proteome during telomere replication

Telomere shortening can cause detrimental diseases and contribute to aging. It occurs due to the end replication problem in cells lacking telomerase. Furthermore, recent studies revealed that telomere shortening can be attributed to difficulties of the semi-conservative DNA replication machinery to...

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Detalles Bibliográficos
Autores principales: Lin, Chih-Yi Gabriela, Näger, Anna Christina, Lunardi, Thomas, Vančevska, Aleksandra, Lossaint, Gérald, Lingner, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643687/
https://www.ncbi.nlm.nih.gov/pubmed/34747482
http://dx.doi.org/10.1093/nar/gkab1015