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Inhibition of SARS-CoV-2 coronavirus proliferation by designer antisense-circRNAs

Circular RNAs (circRNAs) are noncoding RNAs that exist in all eukaryotes investigated and are derived from back-splicing of certain pre-mRNA exons. Here, we report the application of artificial circRNAs designed to act as antisense-RNAs. We systematically tested a series of antisense-circRNAs target...

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Detalles Bibliográficos
Autores principales: Pfafenrot, Christina, Schneider, Tim, Müller, Christin, Hung, Lee-Hsueh, Schreiner, Silke, Ziebuhr, John, Bindereif, Albrecht
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643703/
https://www.ncbi.nlm.nih.gov/pubmed/34850109
http://dx.doi.org/10.1093/nar/gkab1096