Relaxed 3D genome conformation facilitates the pluripotent to totipotent-like state transition in embryonic stem cells

The 3D genome organization is crucial for gene regulation. Although recent studies have revealed a uniquely relaxed genome conformation in totipotent early blastomeres of both fertilized and cloned embryos, how weakened higher-order chromatin structure is functionally linked to totipotency acquisiti...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Yezhang, Yu, Jiali, Gu, Jiahui, Xue, Chaoran, Zhang, Long, Chen, Jiekai, Shen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643704/
https://www.ncbi.nlm.nih.gov/pubmed/34791385
http://dx.doi.org/10.1093/nar/gkab1069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643704/
https://www.ncbi.nlm.nih.gov/pubmed/34791385
http://dx.doi.org/10.1093/nar/gkab1069

Ejemplares similares