199. Polymorphisms in Key Regulatory Regions of the bla operon Correlate with the Cefazolin Inoculum Effect in Methicillin-Susceptible Staphylococcus aureus (MSSA)

BACKGROUND: The cefazolin inoculum effect (CzIE), defined as Cz minimum inhibitory concentration ≥ 16 µg/ml at high inoculum (HI-MIC), has been associated with poor clinical outcomes in patients with MSSA bacteremia or osteomyelitis. The CzIE is correlated with the presence of the blaZ gene, one of...

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Detalles Bibliográficos
Autores principales: Gomez-Villegas, Sara I, Rios, Rafael, Diaz, Lorena, Dinh, An Q, Panesso, Diana, Rincon, Sandra, Carvajal, Lina P, Reyes, Maria I, Murray, Barbara E, Miller, William R, Singh, Kavindra V, Reyes, Jinnethe, Arias, Cesar A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Oral Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643731/
http://dx.doi.org/10.1093/ofid/ofab466.199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643731/
http://dx.doi.org/10.1093/ofid/ofab466.199

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