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1048. Double-Blind, Randomized, Placebo-Controlled Phase 2b Multicenter Trial of V160, a Replication-Defective Human Cytomegalovirus (CMV) Vaccine

BACKGROUND: Preventing congenital cytomegalovirus infection (CMVi) is an important unmet need. Natural maternal immunity to CMV acquired prior to pregnancy appears to reduce fetal transmission. In a Phase 1 trial, V160, a replication-defective CMV vaccine expressing the pentameric complex, induced h...

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Detalles Bibliográficos
Autores principales: Das, Rituparna, Blazquez-Gamero, Daniel, Bernstein, David I, Gantt, Soren, Bautista, Oliver, Beck, Karen, Conlon, Anthony, Rosenbloom, Daniel, Wang, Dai, Ritter, Michael, Arnold, Beth, Annunziato, Paula, Russell, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643772/
http://dx.doi.org/10.1093/ofid/ofab466.1242