Cargando…

1048. Double-Blind, Randomized, Placebo-Controlled Phase 2b Multicenter Trial of V160, a Replication-Defective Human Cytomegalovirus (CMV) Vaccine

BACKGROUND: Preventing congenital cytomegalovirus infection (CMVi) is an important unmet need. Natural maternal immunity to CMV acquired prior to pregnancy appears to reduce fetal transmission. In a Phase 1 trial, V160, a replication-defective CMV vaccine expressing the pentameric complex, induced h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Das, Rituparna, Blazquez-Gamero, Daniel, Bernstein, David I, Gantt, Soren, Bautista, Oliver, Beck, Karen, Conlon, Anthony, Rosenbloom, Daniel, Wang, Dai, Ritter, Michael, Arnold, Beth, Annunziato, Paula, Russell, Kevin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Poster Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643772/ http://dx.doi.org/10.1093/ofid/ofab466.1242

Ejemplares similares

Phase 1 Clinical Trial of a Replication-Defective Human Cytomegalovirus (CMV) Vaccine
por: Adler, Stuart, et al.
Publicado: (2017)

LB18. An Enveloped Virus-like Particle (eVLP) Cytomegalovirus (CMV) Vaccine Is Immunogenic and Safe: Results of a First-in-Humans Study
por: Gantt, Soren, et al.
Publicado: (2018)

Cytomegalovirus (CMV) Infection and Latency
por: O’Connor, Christine M.
Publicado: (2021)

Correlation of Cytomegalovirus (CMV) Disease Severity and Mortality With CMV Viral Burden in CMV-Seropositive Donor and CMV-Seronegative Solid Organ Transplant Recipients
por: McBride, Jacqueline M, et al.
Publicado: (2019)

Recombinant luciferase-expressing human cytomegalovirus (CMV) for evaluation of CMV inhibitors
por: He, Ran, et al.
Publicado: (2011)

Perinatal Cytomegalovirus Infection
por: Carmona, Alejandra Sandoval, et al.
Publicado: (2022)

Targeting cytomegalovirus (CMV) antigens for GBM immunotherapy
por: Nair, Smita K, et al.
Publicado: (2013)

Cytomegalovirus (CMV) seroprevalence in the adult population of Germany
por: Lachmann, Raskit, et al.
Publicado: (2018)

Acute Cytomegalovirus (CMV) Hepatitis in an Immunocompetent Adult
por: Zahid, Maleeha, et al.
Publicado: (2020)

604 Risk Factors for Cytomegalovirus (CMV) Reactivation in CMV-seropositive Liver Transplant Patients
por: Bruminhent, Jackrapong, et al.
Publicado: (2014)

THE PREVALENCE OF CYTOMEGALOVIRUS (CMV) VIRURIA AMONG HOSPITALIZED CHILDREN AND THE RISK OF CMV ACQUISITION BY NURSES
por: Adler, Stuart P, et al.
Publicado: (1984)

417. Cytomegalovirus (CMV) and Sexually Transmitted infections (STIs) During Pregnancy
por: Geetha Pinninti, Swetha, et al.
Publicado: (2019)

Detection of cytomegalovirus (CMV) by digital PCR in stool samples for the non-invasive diagnosis of CMV gastroenteritis
por: Gu, Jia, et al.
Publicado: (2022)

Notes on the Examination of the Eyes of 1,048 East Cleveland School Children
Publicado: (1907)

Role of postoperative radiotherapy in reducing ipsilateral recurrence in DCIS: an observational study of 1048 cases
por: Corradini, Stefanie, et al.
Publicado: (2018)

Cytomegalovirus Hyper Immunoglobulin for CMV Prophylaxis in Thoracic Transplantation
por: Rea, Federico, et al.
Publicado: (2016)

Detection of Cytomegalovirus (CMV) in Saliva of Congenitally Infected Neonates
por: Wissel, Mark, et al.
Publicado: (2017)

Cytomegalovirus (CMV) Pneumonitis: Cell Tropism, Inflammation, and Immunity
por: Fonseca Brito, Luís, et al.
Publicado: (2019)

Antiviral Treatment of Maternal and Congenital Cytomegalovirus (CMV) Infections
por: Pinninti, Swetha, et al.
Publicado: (2023)

Oral Valganciclovir as a Preemptive Treatment for Cytomegalovirus (CMV) Infection in CMV-Seropositive Liver Transplant Recipients
por: Kim, Jong Man, et al.
Publicado: (2015)

Cytomegalovirus (CMV) immune monitoring with ELISPOT and QuantiFERON-CMV assay in seropositive kidney transplant recipients
por: Lee, Hyeyoung, et al.
Publicado: (2017)

“Targeted” Screening for Cytomegalovirus (CMV)-Related Hearing Loss: It’s Time for Universal CMV Screening in the NICU!
por: Medoro, Alexandra, et al.
Publicado: (2017)

1079. The Risk of Cytomegalovirus (CMV) Infection and Recurrence Among Solid Organ Transplant Recipients
por: Reekie, Joanne, et al.
Publicado: (2020)

Highly quantitative serological detection of anti-cytomegalovirus (CMV) antibodies
por: Burbelo, Peter D, et al.
Publicado: (2009)

Cytomegalovirus (CMV) genotype in allogeneic hematopoietic stem cell transplantation
por: Dieamant, Débora C, et al.
Publicado: (2013)

Human cytomegalovirus (CMV) in Africa: a neglected but important pathogen
por: Bates, Matthew, et al.
Publicado: (2016)

LB17. Randomized Trial to Prevent Congenital Cytomegalovirus (CMV)
por: Hughes, Brenna
Publicado: (2019)

Thrombosis Associated With Cytomegalovirus (CMV) in a Kidney Transplant Recipient
por: Wang, Lin, et al.
Publicado: (2021)

998 Detection of Cytomegalovirus (CMV) in Cerebrospinal Fluid of Infants with Congenital CMV Infection: Is It Worth Doing the Lumbar Puncture?
por: Ouellette, Christopher, et al.
Publicado: (2014)

Diagnostic usefulness of the cytomegalovirus (CMV)-specific T cell-based assay for predicting CMV infection after kidney transplant
por: Kim, Taeeun, et al.
Publicado: (2020)

A Mortality Analysis of Letermovir Prophylaxis for Cytomegalovirus (CMV) in CMV-seropositive Recipients of Allogeneic Hematopoietic Cell Transplantation
por: Ljungman, Per, et al.
Publicado: (2020)

Lack of cytomegalovirus (CMV)-specific cell-mediated immune response using QuantiFERON-CMV assay in CMV-seropositive healthy volunteers: fact not artifact
por: Valle-Arroyo, Jorge, et al.
Publicado: (2020)

1198. Measurement of Pre-transplant Anti-cytomegalovirus (CMV) Immunoglobulin G Titer to Predict Risk of CMV Infection in CMV-seropositive Kidney Transplant Recipients
por: Kirisri, Similan, et al.
Publicado: (2020)

Cytomegalovirus (CMV)-specific cytotoxic T lymphocyte therapy resolve CMV diseases and refractory CMV infections in paediatric recipients of allogeneic haematopoietic stem cell transplantation
por: Wang, Xiaodong, et al.
Publicado: (2021)

The Potential Harm of Cytomegalovirus Infection in Immunocompetent Critically Ill Children
por: Alyazidi, Raidan, et al.
Publicado: (2018)

Latent Cytomegalovirus (CMV) Infection Does Not Detrimentally Alter T Cell Responses in the Healthy Old, But Increased Latent CMV Carriage Is Related to Expanded CMV-Specific T Cells
por: Jackson, Sarah E., et al.
Publicado: (2017)

1048. Weight Gain after Initiation of Anti-Retroviral Therapy in Acute HIV-1
por: Kaur, Harmanpreet, et al.
Publicado: (2020)

Performance of non-invasive prenatal testing for foetal chromosomal abnormalities in 1048 twin pregnancies
por: Cheng, Yuan, et al.
Publicado: (2021)

SG-APSIC1048: Lean management dressing set of service unit at Pattani Hospital
por: Sirijindadirat, Nanthipha, et al.
Publicado: (2023)

Patient-reported outcomes in PROSPECT trial (Alliance N1048) – FOLFOX is not a panacea
por: O'Cathail, Sean M., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_11t7a3g67177chdhrrt3c97vpl