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64. Novel Biomarkers Improve Estimation of Vancomycin Clearance in Critically Ill Children

BACKGROUND: There are a paucity of robust population PK (popPK) models to inform vancomycin (VAN) dosing in critically ill children. The majority of published models incorporate peak/trough data and rely on flawed estimates of renal function. We sought to develop a popPK model for IV VAN in critical...

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Detalles Bibliográficos
Autores principales: Downes, Kevin J, Zuppa, Athena F, Sharova, Anna, Gianchetti, Lauren, Duffey, Emily, Goldstein, Stuart L, Neely, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643886/
http://dx.doi.org/10.1093/ofid/ofab466.064