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1106. Evaluation of Penetration of Cefiderocol into Cerebrospinal Fluid Using a Rat Meningitis Model

BACKGROUND: Central nervous system (CNS) infections caused by Gram-negative bacteria (GNB) are sometimes hard to treat due to antibiotic resistance and difficulty with penetration into cerebrospinal fluid (CSF). Cefiderocol (CFDC) which was approved by the FDA and the EMA in 2019 to 2020 is a sidero...

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Detalles Bibliográficos
Autores principales: Takemura, Miki, Kanazawa, Sachi, Kohira, Naoki, Aoe, Yuki, Morimoto, Atsushi, Horiuchi, Kana, Inoue, Yuji, Yamano, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643901/
http://dx.doi.org/10.1093/ofid/ofab466.1300