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1047. Development of a Next Generation 30(+) Valent Pneumococcal Conjugate Vaccine (VAX-XP) Using Site-Specific Carrier Protein Conjugation

BACKGROUND: Due to the diversity of serotypes, exacerbated by the phenomenon of serotype replacement, there remains an unmet medical need for a pneumococcal conjugate vaccine (PCV) containing additional serotypes. Using a cell-free protein synthesis (CFPS) platform to produce an enhanced carrier pro...

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Detalles Bibliográficos
Autores principales: Behrens, Chris, Fairman, Jeff, Agarwal, Paresh, Arulkumar, Shylaja, Barbanel, Sandrine, Bautista, Leslie, Berges, Aym, Burky, John, Davey, Peter, Grainger, Chris, Guo, Sherry, Iki, Sam, Iverson, Mark, Kapoor, Neeraj, Marcq, Olivier, Migone, Thi-Sau, Pill, Lucy, Sardar, Mohammed, Sauer, Paul, Wassil, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644003/
http://dx.doi.org/10.1093/ofid/ofab466.1241