1275. Dynamics of Enterococcus faecalis Cardiolipin Synthase Gene Expression Reveal Compensatory Roles in Daptomycin Resistance

BACKGROUND: Daptomycin (DAP) is a lipopeptide antibiotic targeting membrane anionic phospholipids (APLs) at the division septum, and resistance (DAP-R) has been associated with activation of the E. faecalis (Efs) LiaFSR response and redistribution of APL microdomains (predicted to contain cardiolipi...

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Detalles Bibliográficos
Autores principales: Nguyen, April, Polamraju, Vinathi, Zhang, Rutan, Tran, Truc T, Panesso, Diana, Khan, Ayesha, Mileykovskaya, Eugenia, Shamoo, Yousif, Xu, Libin, Vitrac, Heidi, Arias, Cesar A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644016/
http://dx.doi.org/10.1093/ofid/ofab466.1467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644016/
http://dx.doi.org/10.1093/ofid/ofab466.1467

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