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1275. Dynamics of Enterococcus faecalis Cardiolipin Synthase Gene Expression Reveal Compensatory Roles in Daptomycin Resistance
BACKGROUND: Daptomycin (DAP) is a lipopeptide antibiotic targeting membrane anionic phospholipids (APLs) at the division septum, and resistance (DAP-R) has been associated with activation of the E. faecalis (Efs) LiaFSR response and redistribution of APL microdomains (predicted to contain cardiolipi...
Autores principales: | Nguyen, April, Polamraju, Vinathi, Zhang, Rutan, Tran, Truc T, Panesso, Diana, Khan, Ayesha, Mileykovskaya, Eugenia, Shamoo, Yousif, Xu, Libin, Vitrac, Heidi, Arias, Cesar A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644016/ http://dx.doi.org/10.1093/ofid/ofab466.1467 |
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