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1120. Absorption, Metabolism, and Excretion of [(14)C]-Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) Following a Single Oral Dose in Healthy Male Subjects

BACKGROUND: Tebipenem pivoxil hydrobromide (TBP-PI-HBr) is an oral prodrug that is converted to tebipenem (TBP), the active moiety, with activity against multidrug-resistant gram-negative pathogens, including extended-spectrum-β-lactamase (ESBL)-producing Enterobacterales. TBP-PI-HBr is the first or...

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Detalles Bibliográficos
Autores principales: Gupta, Vipul K, Maier, Gary, Gasink, Leanne, Ek, Amanda, Fudeman, Mary, Srivastava, Praveen, Talley, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644141/
http://dx.doi.org/10.1093/ofid/ofab466.1313