1246. Clinical isolates of Pseudomonas aeruginosa Harbor Preexisting Changes in TonB-dependent Receptors Associated with Decreased Susceptibility to Cefiderocol

BACKGROUND: Cefiderocol (FDC) is a novel siderophore cephalosporin that retains activity against MDR gram-negative bacteria. In P. aeruginosa (PA), FDC utilizes TonB-dependent receptors (TBDR) PirA, PiuA, or PiuD to enter the periplasmic space. We recently reported a clinical PA isolate that develop...

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Detalles Bibliográficos
Autores principales: Egge, Stephanie L, Simar, Shelby, Dinh, An Q, Hanson, Blake, Tran, Truc T, Arias, Cesar A, Miller, William R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644173/
http://dx.doi.org/10.1093/ofid/ofab466.1438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644173/
http://dx.doi.org/10.1093/ofid/ofab466.1438

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