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1000. Serotype 3 pneumococci evade activation of the classical complement pathway

BACKGROUND: Complement classical pathway (CCP) activation is the major mechanism leading to opsonophagocytic pneumococcal killing. Following immunization with 13-valent pneumococcal conjugate vaccine (PCV13), opsonophagocytic titers are lowest against serotype 3 among the 13 vaccine serotypes. Post...

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Detalles Bibliográficos
Autores principales: Lapidot, Rotem, Ramirez, Mario, Lee, Dayeun, Scully, Ingrid L, Gessner, Bradford D, pelton, stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644190/
http://dx.doi.org/10.1093/ofid/ofab466.1194