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1111. Therapeutic Drug Monitoring of Colistin in Cerebrospinal Fluid in the Treatment of Neurosurgical Meningitis caused by Pseudomonas aeruginosa and KPC-producing Enterobacterales

BACKGROUND: Central nervous system (CNS) infections caused by carbapenem-resistant Enterobacterales (CRE) and Difficult-to-treat resistant (DTR)-P. aeruginosa (PA) present a therapeutic dilemma. Therapies are limited due to antibiotic resistance and inadequate CNS diffusion. Intraventricular polymyx...

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Detalles Bibliográficos
Autores principales: Yasmin, Mohamad, nutman, Amir, Marshall, Steven, Wang, Lu, Chen, Ke, Yahav, Dafna, Wang, Jiping, Li, Jian, Bonomo, Robert A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644291/
http://dx.doi.org/10.1093/ofid/ofab466.1305